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Cortical binding of Pittsburgh compound B, an endophenotype for genetic studies of Alzheimer's disease
BACKGROUND: To date, all known Alzheimer's disease genes influence amyloid beta (Aβ). The development of in vivo imaging of Aβ deposition in the human brain using Pittsburgh compound B (PIB) offers the possibility of using cortical PIB binding as a quantitative endophenotype for genetic studies...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2866645/ https://ncbi.nlm.nih.gov/pubmed/19892322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.09.012 |
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