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Discovery and Characterization of Novel GPR39 Agonists Allosterically Modulated by Zinc

In this study, we identified two previously described kinase inhibitors—3-(4-chloro-2-fluorobenzyl)-2-methyl-N-(3-methyl-1H-pyrazol-5-yl)-8-(morpholinomethyl)imidazo[1,2-b]pyridazin-6-amine (LY2784544) and 1H-benzimidazole-4-carboxylic acid, 2-methyl-1-[[2-methyl-3-(trifluoromethyl)phenyl]methyl]-6-...

詳細記述

保存先:
書誌詳細
出版年:Mol Pharmacol
主要な著者: Sato, Seiji, Huang, Xi-Ping, Kroeze, Wesley K., Roth, Bryan L.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Pharmacology and Experimental Therapeutics 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118639/
https://ncbi.nlm.nih.gov/pubmed/27754899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.106112
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