The lipid sensor GPR120 promotes brown fat activation and FGF21 release from adipocytes

The thermogenic activity of brown adipose tissue (BAT) and browning of white adipose tissue are important components of energy expenditure. Here we show that GPR120, a receptor for polyunsaturated fatty acids, promotes brown fat activation. Using RNA-seq to analyse mouse BAT transcriptome, we find t...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Quesada-López, Tania, Cereijo, Rubén, Turatsinze, Jean-Valery, Planavila, Anna, Cairó, Montserrat, Gavaldà-Navarro, Aleix, Peyrou, Marion, Moure, Ricardo, Iglesias, Roser, Giralt, Marta, Eizirik, Decio L., Villarroya, Francesc
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118546/
https://ncbi.nlm.nih.gov/pubmed/27853148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13479
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