The lipid sensor GPR120 promotes brown fat activation and FGF21 release from adipocytes

The thermogenic activity of brown adipose tissue (BAT) and browning of white adipose tissue are important components of energy expenditure. Here we show that GPR120, a receptor for polyunsaturated fatty acids, promotes brown fat activation. Using RNA-seq to analyse mouse BAT transcriptome, we find t...

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Pubblicato in:Nat Commun
Autori principali: Quesada-López, Tania, Cereijo, Rubén, Turatsinze, Jean-Valery, Planavila, Anna, Cairó, Montserrat, Gavaldà-Navarro, Aleix, Peyrou, Marion, Moure, Ricardo, Iglesias, Roser, Giralt, Marta, Eizirik, Decio L., Villarroya, Francesc
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118546/
https://ncbi.nlm.nih.gov/pubmed/27853148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13479
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