Aging is associated with increased FGF21 levels but unaltered FGF21 responsiveness in adipose tissue

Fibroblast growth factor 21 (FGF21) has been proposed to be an antiaging hormone on the basis of experimental studies in rodent models. However, circulating FGF21 levels are increased with aging in rodents and humans. Moreover, despite the metabolic health‐promoting effects of FGF21, the levels of t...

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Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Villarroya, Joan, Gallego‐Escuredo, José M., Delgado‐Anglés, Alejando, Cairó, Montserrat, Moure, Ricardo, Gracia Mateo, Ma, Domingo, Joan C., Domingo, Pere, Giralt, Marta, Villarroya, Francesc
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Short Take
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156525/
https://ncbi.nlm.nih.gov/pubmed/30043445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12822
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