Aging is associated with increased FGF21 levels but unaltered FGF21 responsiveness in adipose tissue

Fibroblast growth factor 21 (FGF21) has been proposed to be an antiaging hormone on the basis of experimental studies in rodent models. However, circulating FGF21 levels are increased with aging in rodents and humans. Moreover, despite the metabolic health‐promoting effects of FGF21, the levels of t...

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發表在:Aging Cell
Main Authors: Villarroya, Joan, Gallego‐Escuredo, José M., Delgado‐Anglés, Alejando, Cairó, Montserrat, Moure, Ricardo, Gracia Mateo, Ma, Domingo, Joan C., Domingo, Pere, Giralt, Marta, Villarroya, Francesc
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156525/
https://ncbi.nlm.nih.gov/pubmed/30043445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12822
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