Aging is associated with increased FGF21 levels but unaltered FGF21 responsiveness in adipose tissue

Fibroblast growth factor 21 (FGF21) has been proposed to be an antiaging hormone on the basis of experimental studies in rodent models. However, circulating FGF21 levels are increased with aging in rodents and humans. Moreover, despite the metabolic health‐promoting effects of FGF21, the levels of t...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Villarroya, Joan, Gallego‐Escuredo, José M., Delgado‐Anglés, Alejando, Cairó, Montserrat, Moure, Ricardo, Gracia Mateo, Ma, Domingo, Joan C., Domingo, Pere, Giralt, Marta, Villarroya, Francesc
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Short Take
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156525/
https://ncbi.nlm.nih.gov/pubmed/30043445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12822
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