Parkin controls brown adipose tissue plasticity in response to adaptive thermogenesis

Parkin is an ubiquitin‐E3 ligase that acts as a key component of the cellular machinery for mitophagy. We show here that Parkin expression is reciprocally regulated in brown adipose tissue in relation to thermogenic activity. Thermogenic stimuli repress Parkin gene expression via transcriptional mec...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO Rep
Egile Nagusiak: Cairó, Montserrat, Campderrós, Laura, Gavaldà‐Navarro, Aleix, Cereijo, Rubén, Delgado‐Anglés, Alejandro, Quesada‐López, Tania, Giralt, Marta, Villarroya, Joan, Villarroya, Francesc
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501052/
https://ncbi.nlm.nih.gov/pubmed/30867164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201846832
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