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Parkin controls brown adipose tissue plasticity in response to adaptive thermogenesis
Parkin is an ubiquitin‐E3 ligase that acts as a key component of the cellular machinery for mitophagy. We show here that Parkin expression is reciprocally regulated in brown adipose tissue in relation to thermogenic activity. Thermogenic stimuli repress Parkin gene expression via transcriptional mec...
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| Pubblicato in: | EMBO Rep |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6501052/ https://ncbi.nlm.nih.gov/pubmed/30867164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201846832 |
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