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Parkin controls brown adipose tissue plasticity in response to adaptive thermogenesis

Parkin is an ubiquitin‐E3 ligase that acts as a key component of the cellular machinery for mitophagy. We show here that Parkin expression is reciprocally regulated in brown adipose tissue in relation to thermogenic activity. Thermogenic stimuli repress Parkin gene expression via transcriptional mec...

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Bibliografski detalji
Izdano u:EMBO Rep
Glavni autori: Cairó, Montserrat, Campderrós, Laura, Gavaldà‐Navarro, Aleix, Cereijo, Rubén, Delgado‐Anglés, Alejandro, Quesada‐López, Tania, Giralt, Marta, Villarroya, Joan, Villarroya, Francesc
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501052/
https://ncbi.nlm.nih.gov/pubmed/30867164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201846832
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