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Parkin controls brown adipose tissue plasticity in response to adaptive thermogenesis
Parkin is an ubiquitin‐E3 ligase that acts as a key component of the cellular machinery for mitophagy. We show here that Parkin expression is reciprocally regulated in brown adipose tissue in relation to thermogenic activity. Thermogenic stimuli repress Parkin gene expression via transcriptional mec...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6501052/ https://ncbi.nlm.nih.gov/pubmed/30867164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201846832 |
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