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TWEAK-Fn14 Signaling Activates Myofibroblasts to Drive Progression of Fibrotic Kidney Disease

The identification of the cellular origins of myofibroblasts has led to the discovery of novel pathways that potentially drive myofibroblast perpetuation in disease. Here, we further investigated the role of innate immune signaling pathways in this process. In mice, renal injury-induced activation o...

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Detalles Bibliográficos
Publicado en:J Am Soc Nephrol
Autores principales: Gomez, Ivan G., Roach, Allie M., Nakagawa, Naoki, Amatucci, Aldo, Johnson, Bryce G., Dunn, Kadeshia, Kelly, Mark C., Karaca, Gamze, Zheng, Timothy S., Szak, Suzanne, Peppiatt-Wildman, Claire M., Burkly, Linda C., Duffield, Jeremy S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118488/
https://ncbi.nlm.nih.gov/pubmed/27026366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015111227
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