TWEAK-Fn14 Signaling Activates Myofibroblasts to Drive Progression of Fibrotic Kidney Disease

The identification of the cellular origins of myofibroblasts has led to the discovery of novel pathways that potentially drive myofibroblast perpetuation in disease. Here, we further investigated the role of innate immune signaling pathways in this process. In mice, renal injury-induced activation o...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Gomez, Ivan G., Roach, Allie M., Nakagawa, Naoki, Amatucci, Aldo, Johnson, Bryce G., Dunn, Kadeshia, Kelly, Mark C., Karaca, Gamze, Zheng, Timothy S., Szak, Suzanne, Peppiatt-Wildman, Claire M., Burkly, Linda C., Duffield, Jeremy S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118488/
https://ncbi.nlm.nih.gov/pubmed/27026366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015111227
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