Reduced blood pressure after smooth muscle EFNB2 deletion and the potential association of EFNB2 mutation with human hypertension risk

Ephrin B2 (EFNB2) is a ligand for erythropoietin-producing hepatocellular kinases (EPH), the largest family of receptor tyrosine kinases. It has critical functions in many biological systems, but is not known to regulate blood pressure. We generated mice with a smooth muscle cell (SMC)-specific dele...

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Detaylı Bibliyografya
Yayımlandı:Eur J Hum Genet
Asıl Yazarlar: Wang, Yujia, Hamet, Pavel, Thorin, Eric, Tremblay, Johanne, Raelson, John, Wu, Zenghui, Luo, Hongyu, Jin, Wei, Lavoie, Julie L, Peng, Junzheng, Marois-Blanchet, Francois-Christophe, Tahir, Muhammad Ramzan, Chalmers, John, Woodward, Mark, Harrap, Stephen, Qi, Shijie, Li, Charles Yibin, Wu, Jiangping
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117913/
https://ncbi.nlm.nih.gov/pubmed/27530629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2016.105
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