Estrogen and testosterone in concert with EFNB3 regulate vascular smooth muscle cell contractility and blood pressure

EPH kinases and their ligands, ephrins (EFNs), have vital and diverse biological functions, although their function in blood pressure (BP) control has not been studied in detail. In the present study, we report that Efnb3 gene knockout (KO) led to increased BP in female but not male mice. Vascular s...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Wang, Yujia, Wu, Zenghui, Thorin, Eric, Tremblay, Johanne, Lavoie, Julie L., Luo, Hongyu, Peng, Junzheng, Qi, Shijie, Wu, Tao, Chen, Fei, Shen, Jianzhong, Hu, Shenjiang, Wu, Jiangping
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Vascular Biology and Microcirculation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867358/
https://ncbi.nlm.nih.gov/pubmed/26851246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00873.2015
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