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Estrogen and testosterone in concert with EFNB3 regulate vascular smooth muscle cell contractility and blood pressure

EPH kinases and their ligands, ephrins (EFNs), have vital and diverse biological functions, although their function in blood pressure (BP) control has not been studied in detail. In the present study, we report that Efnb3 gene knockout (KO) led to increased BP in female but not male mice. Vascular s...

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Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: Wang, Yujia, Wu, Zenghui, Thorin, Eric, Tremblay, Johanne, Lavoie, Julie L., Luo, Hongyu, Peng, Junzheng, Qi, Shijie, Wu, Tao, Chen, Fei, Shen, Jianzhong, Hu, Shenjiang, Wu, Jiangping
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867358/
https://ncbi.nlm.nih.gov/pubmed/26851246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00873.2015
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