Reduced blood pressure after smooth muscle EFNB2 deletion and the potential association of EFNB2 mutation with human hypertension risk

Ephrin B2 (EFNB2) is a ligand for erythropoietin-producing hepatocellular kinases (EPH), the largest family of receptor tyrosine kinases. It has critical functions in many biological systems, but is not known to regulate blood pressure. We generated mice with a smooth muscle cell (SMC)-specific dele...

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Udgivet i:Eur J Hum Genet
Main Authors: Wang, Yujia, Hamet, Pavel, Thorin, Eric, Tremblay, Johanne, Raelson, John, Wu, Zenghui, Luo, Hongyu, Jin, Wei, Lavoie, Julie L, Peng, Junzheng, Marois-Blanchet, Francois-Christophe, Tahir, Muhammad Ramzan, Chalmers, John, Woodward, Mark, Harrap, Stephen, Qi, Shijie, Li, Charles Yibin, Wu, Jiangping
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117913/
https://ncbi.nlm.nih.gov/pubmed/27530629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2016.105
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