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Evidence from single nucleotide polymorphism analyses of ADVANCE study demonstrates EFNB3 as a hypertension risk gene

EPH kinases and their ligands, ephrins (EFNs), have vital and diverse biological functions. We recently reported that Efnb3 gene deletion results in hypertension in female but not male mice. These data suggest that EFNB3 regulates blood pressure in a sex- and sex hormone-dependent way. In the presen...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Tremblay, Johanne, Wang, Yujia, Raelson, John, Marois-Blanchet, Francois-Christophe, Wu, Zenghui, Luo, Hongyu, Bradley, Edward, Chalmers, John, Woodward, Mark, Harrap, Stephen, Hamet, Pavel, Wu, Jiangping
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341021/
https://ncbi.nlm.nih.gov/pubmed/28272517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44114
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