Discovery of MRSA active antibiotics using primary sequence from the human microbiome

Here, we present a natural product discovery approach whereby structures are bioinformatically predicted from primary sequence and produced by chemical synthesis (synthetic-bioinformatic natural products, syn-BNPs), circumventing the need for bacterial culture and gene expression. When applied to no...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Nat Chem Biol
Asıl Yazarlar: Chu, John, Vila-Farres, Xavier, Inoyama, Daigo, Ternei, Melinda, Cohen, Louis J., Gordon, Emma A., Reddy, Boojala Vijay B., Charlop-Powers, Zachary, Zebroski, Henry A., Gallardo-Macias, Ricardo, Jaskowski, Mark, Satish, Shruthi, Park, Steven, Perlin, David S., Freundlich, Joel S., Brady, Sean F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117632/
https://ncbi.nlm.nih.gov/pubmed/27748750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2207
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller