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Aag Hypoxanthine-DNA Glycosylase Is Synthesized in the Forespore Compartment and Involved in Counteracting the Genotoxic and Mutagenic Effects of Hypoxanthine and Alkylated Bases in DNA during Bacillus subtilis Sporulation

Aag from Bacillus subtilis has been implicated in in vitro removal of hypoxanthine and alkylated bases from DNA. The regulation of expression of aag in B. subtilis and the resistance to genotoxic agents and mutagenic properties of an Aag-deficient strain were studied here. A strain with a transcript...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Ayala-García, Víctor M., Valenzuela-García, Luz I., Setlow, Peter, Pedraza-Reyes, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116938/
https://ncbi.nlm.nih.gov/pubmed/27698084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00625-16
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