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Aag Hypoxanthine-DNA Glycosylase Is Synthesized in the Forespore Compartment and Involved in Counteracting the Genotoxic and Mutagenic Effects of Hypoxanthine and Alkylated Bases in DNA during Bacillus subtilis Sporulation

Aag from Bacillus subtilis has been implicated in in vitro removal of hypoxanthine and alkylated bases from DNA. The regulation of expression of aag in B. subtilis and the resistance to genotoxic agents and mutagenic properties of an Aag-deficient strain were studied here. A strain with a transcript...

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Dettagli Bibliografici
Pubblicato in:J Bacteriol
Autori principali: Ayala-García, Víctor M., Valenzuela-García, Luz I., Setlow, Peter, Pedraza-Reyes, Mario
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116938/
https://ncbi.nlm.nih.gov/pubmed/27698084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00625-16
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