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Thirty-Eight-Year Follow-Up of Two Sibling Lipoid Congenital Adrenal Hyperplasia Patients Due to Homozygous Steroidogenic Acute Regulatory (STARD1) Protein Mutation. Molecular Structure and Modeling of the STARD1 L275P Mutation

Objective: Review the impact of StAR (STARD1) mutations on steroidogenesis and fertility in LCAH patients. Examine the endocrine mechanisms underlying the pathology of the disorder and the appropriate therapy for promoting fertility and pregnancies. Design: Published data in the literature and a det...

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Dades bibliogràfiques
Publicat a:Front Neurosci
Autors principals: Khoury, Khalil, Barbar, Elie, Ainmelk, Youssef, Ouellet, Annie, Lavigne, Pierre, LeHoux, Jean-Guy
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116571/
https://ncbi.nlm.nih.gov/pubmed/27917104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00527
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