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STARD6 on steroids: solution structure, multiple timescale backbone dynamics and ligand binding mechanism

START domain proteins are conserved α/β helix-grip fold that play a role in the non-vesicular and intracellular transport of lipids and sterols. The mechanism and conformational changes permitting the entry of the ligand into their buried binding sites is not well understood. Moreover, their functio...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Létourneau, Danny, Bédard, Mikaël, Cabana, Jérôme, Lefebvre, Andrée, LeHoux, Jean-Guy, Lavigne, Pierre
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919784/
https://ncbi.nlm.nih.gov/pubmed/27340016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28486
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