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STARD6 on steroids: solution structure, multiple timescale backbone dynamics and ligand binding mechanism
START domain proteins are conserved α/β helix-grip fold that play a role in the non-vesicular and intracellular transport of lipids and sterols. The mechanism and conformational changes permitting the entry of the ligand into their buried binding sites is not well understood. Moreover, their functio...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4919784/ https://ncbi.nlm.nih.gov/pubmed/27340016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28486 |
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