Loss of dopaminergic nigrostriatal neurons accounts for the motivational and affective deficits in Parkinson's disease

Parkinson’s Disease (PD) involves the degeneration of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc) that is thought to cause the classical motor symptoms of this disease. However, motivational and affective impairments are also often observed in PD patients. These are usually...

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Publicat a:Mol Psychiatry
Autors principals: Drui, Guillaume, Carnicella, Sébastien, Carcenac, Carole, Favier, Matthieu, Bertrand, Anne, Boulet, Sabrina, Savasta, Marc
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group Specialist Journals 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116056/
https://ncbi.nlm.nih.gov/pubmed/23399912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2013.3
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