Loss of dopaminergic nigrostriatal neurons accounts for the motivational and affective deficits in Parkinson's disease

Parkinson’s Disease (PD) involves the degeneration of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc) that is thought to cause the classical motor symptoms of this disease. However, motivational and affective impairments are also often observed in PD patients. These are usually...

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Veröffentlicht in:Mol Psychiatry
Hauptverfasser: Drui, Guillaume, Carnicella, Sébastien, Carcenac, Carole, Favier, Matthieu, Bertrand, Anne, Boulet, Sabrina, Savasta, Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group Specialist Journals 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116056/
https://ncbi.nlm.nih.gov/pubmed/23399912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2013.3
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