Loss of dopaminergic nigrostriatal neurons accounts for the motivational and affective deficits in Parkinson's disease

Parkinson’s Disease (PD) involves the degeneration of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc) that is thought to cause the classical motor symptoms of this disease. However, motivational and affective impairments are also often observed in PD patients. These are usually...

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Bibliographic Details
Published in:Mol Psychiatry
Main Authors: Drui, Guillaume, Carnicella, Sébastien, Carcenac, Carole, Favier, Matthieu, Bertrand, Anne, Boulet, Sabrina, Savasta, Marc
Format: Artigo
Language:Inglês
Published: Nature Publishing Group Specialist Journals 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116056/
https://ncbi.nlm.nih.gov/pubmed/23399912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2013.3
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