Implication of dorsostriatal D3 receptors in motivational processes: a potential target for neuropsychiatric symptoms in Parkinson’s disease

Beyond classical motor symptoms, motivational and affective deficits are frequently observed in Parkinson’s disease (PD), dramatically impairing the quality of life of patients. Using bilateral 6-hydroxydopamine (6-OHDA) lesions of the substantia nigra pars compacta (SNc) in rats, we have been able...

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Publicat a:Sci Rep
Autors principals: Favier, Mathieu, Carcenac, Carole, Drui, Guillaume, Vachez, Yvan, Boulet, Sabrina, Savasta, Marc, Carnicella, Sebastien
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278505/
https://ncbi.nlm.nih.gov/pubmed/28134302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41589
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