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Inorganic polyphosphate promotes cyclin D1 synthesis through activation of mTOR/Wnt/β-catenin signaling in endothelial cells
BACKGROUND: Inorganic polyphosphate (polyP) elicits intracellular signaling responses in endothelial cells through activation of mTOR complexes 1 and 2. Glycogen synthase kinase 3 (GSK-3) is known to be a negative regulator of mTOR and Wnt/β-catenin signaling pathways. OBJECTIVE: The objective of th...
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| Publicat a: | J Thromb Haemost |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5116009/ https://ncbi.nlm.nih.gov/pubmed/27546592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13477 |
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