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Inorganic polyphosphate elicits proinflammatory responses through activation of mTOR complexes 1 and 2 in vascular endothelial cells

BACKGROUND: Inorganic polyphosphate (polyP) elicits proinflammatory signaling responses in endothelial cells through interaction with two receptors, RAGE and P2Y(1). It is known that polyP activates mTOR signaling in breast cancer cells. OBJECTIVES: The objective of this study is to understand the m...

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Bibliografiske detaljer
Udgivet i:J Thromb Haemost
Main Authors: Hassanian, Seyed Mahdi, Dinarvand, Peyman, Smith, Stephanie A., Rezaie, Alireza R.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424178/
https://ncbi.nlm.nih.gov/pubmed/25776944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12899
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