Inorganic polyphosphate elicits proinflammatory responses through activation of mTOR complexes 1 and 2 in vascular endothelial cells

BACKGROUND: Inorganic polyphosphate (polyP) elicits proinflammatory signaling responses in endothelial cells through interaction with two receptors, RAGE and P2Y(1). It is known that polyP activates mTOR signaling in breast cancer cells. OBJECTIVES: The objective of this study is to understand the m...

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Veröffentlicht in:J Thromb Haemost
Hauptverfasser: Hassanian, Seyed Mahdi, Dinarvand, Peyman, Smith, Stephanie A., Rezaie, Alireza R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424178/
https://ncbi.nlm.nih.gov/pubmed/25776944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12899
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