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Inorganic polyphosphate elicits proinflammatory responses through activation of mTOR complexes 1 and 2 in vascular endothelial cells

BACKGROUND: Inorganic polyphosphate (polyP) elicits proinflammatory signaling responses in endothelial cells through interaction with two receptors, RAGE and P2Y(1). It is known that polyP activates mTOR signaling in breast cancer cells. OBJECTIVES: The objective of this study is to understand the m...

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Publicado en:J Thromb Haemost
Main Authors: Hassanian, Seyed Mahdi, Dinarvand, Peyman, Smith, Stephanie A., Rezaie, Alireza R.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424178/
https://ncbi.nlm.nih.gov/pubmed/25776944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12899
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