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Inorganic polyphosphate elicits proinflammatory responses through activation of mTOR complexes 1 and 2 in vascular endothelial cells

BACKGROUND: Inorganic polyphosphate (polyP) elicits proinflammatory signaling responses in endothelial cells through interaction with two receptors, RAGE and P2Y(1). It is known that polyP activates mTOR signaling in breast cancer cells. OBJECTIVES: The objective of this study is to understand the m...

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Pubblicato in:J Thromb Haemost
Autori principali: Hassanian, Seyed Mahdi, Dinarvand, Peyman, Smith, Stephanie A., Rezaie, Alireza R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424178/
https://ncbi.nlm.nih.gov/pubmed/25776944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12899
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