Inorganic polyphosphate promotes cyclin D1 synthesis through activation of mTOR/Wnt/β-catenin signaling in endothelial cells

BACKGROUND: Inorganic polyphosphate (polyP) elicits intracellular signaling responses in endothelial cells through activation of mTOR complexes 1 and 2. Glycogen synthase kinase 3 (GSK-3) is known to be a negative regulator of mTOR and Wnt/β-catenin signaling pathways. OBJECTIVE: The objective of th...

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Vydáno v:J Thromb Haemost
Hlavní autoři: Hassanian, Seyed Mahdi, Ardeshirylajimi, Abdolreza, Dinarvand, Peyman, Rezaie, Alireza R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116009/
https://ncbi.nlm.nih.gov/pubmed/27546592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13477
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