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Ribosome-based quality control of mRNA and nascent peptides

Quality control processes are widespread and play essential roles in detecting defective molecules and removing them in order to maintain organismal fitness. Aberrant mRNA molecules, unless properly managed, pose a significant hurdle to cellular proteostasis. Often mRNAs harbor premature stop codons...

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Bibliografiske detaljer
Udgivet i:Wiley Interdiscip Rev RNA
Main Authors: Simms, Carrie L., Thomas, Erica N., Zaher, Hani S.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116004/
https://ncbi.nlm.nih.gov/pubmed/27193249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1366
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