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An active role for the ribosome in determining the fate of oxidized mRNA

Chemical damage to RNA affects its functional properties and hence may pose a significant hurdle to the translational apparatus; however, the effects of damaged mRNA on the speed and accuracy of the decoding process and their interplay with quality control processes are not known. Here, we systemati...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Simms, Carrie L., Hudson, Benjamin H., Mosior, John W., Rangwala, Ali S., Zaher, Hani S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254665/
https://ncbi.nlm.nih.gov/pubmed/25456128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.10.042
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