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An Mcm10 mutant defective in ssDNA binding shows defects in DNA replication initiation
Mcm10 is an essential protein that functions to initiate DNA replication after the formation of the replication fork helicase. In this manuscript, we identified a budding yeast Mcm10 mutant (Mcm10-m2,3,4) that is defective in DNA binding in vitro. Moreover, this Mcm10-m2,3,4 mutant does not stimulat...
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| Udgivet i: | J Mol Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5115986/ https://ncbi.nlm.nih.gov/pubmed/27751725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.10.014 |
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