Structural Basis for DNA Binding by Replication Initiator Mcm10

Mcm10 is an essential eukaryotic DNA replication protein required for assembly and progression of the replication fork. The highly conserved internal domain (Mcm10-ID) has been shown to physically interact with single-stranded (ss) DNA, DNA polymerase α, and PCNA. The crystal structure of Xenopus la...

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Main Authors: Warren, Eric M., Vaithiyalingam, Sivaraja, Haworth, Justin, Greer, Briana, Bielinsky, Anja-Katrin, Chazin, Walter J., Eichman, Brandt F.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636851/
https://ncbi.nlm.nih.gov/pubmed/19081065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.10.005
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