Caricamento...
RNAi prevents and reverses phenotypes induced by mutant human ataxin‐1
OBJECTIVE: Spinocerebellar ataxia type 1 is an autosomal dominant fatal neurodegenerative disease caused by a polyglutamine expansion in the coding region of ATXN1. We showed previously that partial suppression of mutant ataxin‐1 (ATXN1) expression, using virally expressed RNAi triggers, could preve...
Salvato in:
| Pubblicato in: | Ann Neurol |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2016
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5115960/ https://ncbi.nlm.nih.gov/pubmed/27686464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24789 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|