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Broad distribution of ataxin 1 silencing in rhesus cerebella for spinocerebellar ataxia type 1 therapy

Spinocerebellar ataxia type 1 is one of nine polyglutamine expansion diseases and is characterized by cerebellar ataxia and neuronal degeneration in the cerebellum and brainstem. Currently, there are no effective therapies for this disease. Previously, we have shown that RNA interference mediated si...

詳細記述

保存先:
書誌詳細
出版年:Brain
主要な著者: Keiser, Megan S., Kordower, Jeffrey H., Gonzalez-Alegre, Pedro, Davidson, Beverly L.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840549/
https://ncbi.nlm.nih.gov/pubmed/26490326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv292
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