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Broad distribution of ataxin 1 silencing in rhesus cerebella for spinocerebellar ataxia type 1 therapy

Spinocerebellar ataxia type 1 is one of nine polyglutamine expansion diseases and is characterized by cerebellar ataxia and neuronal degeneration in the cerebellum and brainstem. Currently, there are no effective therapies for this disease. Previously, we have shown that RNA interference mediated si...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Brain
Päätekijät: Keiser, Megan S., Kordower, Jeffrey H., Gonzalez-Alegre, Pedro, Davidson, Beverly L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840549/
https://ncbi.nlm.nih.gov/pubmed/26490326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv292
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