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Role of E2- RING interactions in governing RNF4-mediated substrate ubiquitination

Members of the RING E3 ubiquitin ligase family bind to both substrate and ubiquitin-charged E2 enzyme, promoting transfer of ubiquitin from the E2 to substrate. Either a single ubiquitin or one of several types of polyubiquitin chains can be conjugated to substrate proteins, with different types of...

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Detalles Bibliográficos
Publicado en:J Mol Biol
Main Authors: DiBello, Anthony, Datta, Ajit B., Zhang, Xiangbin, Wolberger, Cynthia
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115946/
https://ncbi.nlm.nih.gov/pubmed/27678051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.09.018
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