Impaired autophagy activity is linked to elevated ER-stress and inflammation in aging adipose tissue

Adipose tissue dysfunction in aging is associated with inflammation, metabolic syndrome and other diseases. We propose that impaired protein homeostasis due to compromised lysosomal degradation (micro-autophagy) might promote aberrant ER stress response and inflammation in aging adipose tissue. Usin...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Ghosh, Amiya Kumar, Mau, Theresa, O'Brien, Martin, Garg, Sanjay, Yung, Raymond
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115904/
https://ncbi.nlm.nih.gov/pubmed/27777379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101083
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