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AUTOPHAGY ACTIVITY IS LINKED TO ELEVATED ER-STRESS AND INFLAMMATION IN AGING ADIPOSE TISSUE
Adipose tissue dysfunction in aging is associated with inflammation, metabolic syndrome and other diseases. We propose that impaired protein homeostasis due to compromised lysosomal degradation (micro-autophagy) might promote aberrant ER stress response and inflammation in aging adipose tissue. Usin...
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| Publicado no: | Innov Aging |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6184911/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.3535 |
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