AUTOPHAGY ACTIVITY IS LINKED TO ELEVATED ER-STRESS AND INFLAMMATION IN AGING ADIPOSE TISSUE

Adipose tissue dysfunction in aging is associated with inflammation, metabolic syndrome and other diseases. We propose that impaired protein homeostasis due to compromised lysosomal degradation (micro-autophagy) might promote aberrant ER stress response and inflammation in aging adipose tissue. Usin...

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Bibliographic Details
Published in:Innov Aging
Main Authors: Ghosh, A.K., Mau, T., O’Brien, M., Yung, R.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6184911/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.3535
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