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Impaired autophagy activity is linked to elevated ER-stress and inflammation in aging adipose tissue
Adipose tissue dysfunction in aging is associated with inflammation, metabolic syndrome and other diseases. We propose that impaired protein homeostasis due to compromised lysosomal degradation (micro-autophagy) might promote aberrant ER stress response and inflammation in aging adipose tissue. Usin...
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| Pubblicato in: | Aging (Albany NY) |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5115904/ https://ncbi.nlm.nih.gov/pubmed/27777379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101083 |
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