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Impaired autophagy activity is linked to elevated ER-stress and inflammation in aging adipose tissue

Adipose tissue dysfunction in aging is associated with inflammation, metabolic syndrome and other diseases. We propose that impaired protein homeostasis due to compromised lysosomal degradation (micro-autophagy) might promote aberrant ER stress response and inflammation in aging adipose tissue. Usin...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Ghosh, Amiya Kumar, Mau, Theresa, O'Brien, Martin, Garg, Sanjay, Yung, Raymond
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115904/
https://ncbi.nlm.nih.gov/pubmed/27777379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101083
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