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Impaired autophagy activity is linked to elevated ER-stress and inflammation in aging adipose tissue
Adipose tissue dysfunction in aging is associated with inflammation, metabolic syndrome and other diseases. We propose that impaired protein homeostasis due to compromised lysosomal degradation (micro-autophagy) might promote aberrant ER stress response and inflammation in aging adipose tissue. Usin...
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| Опубликовано в: : | Aging (Albany NY) |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Impact Journals LLC
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5115904/ https://ncbi.nlm.nih.gov/pubmed/27777379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101083 |
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