A Genetic Algorithm for Diploid Genome Reconstruction Using Paired-End Sequencing

The genome of many species in the biosphere is a diploid consisting of paternal and maternal haplotypes. The differences between these two haplotypes range from single nucleotide polymorphisms (SNPs) to large-scale structural variations (SVs). Existing genome assemblers for next-generation sequencin...

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Udgivet i:PLoS One
Main Authors: Ting, Chuan-Kang, Lin, Choun-Sea, Chan, Ming-Tsai, Chen, Jian-Wei, Chuang, Sheng-Yu, Huang, Yao-Ting
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115803/
https://ncbi.nlm.nih.gov/pubmed/27861560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166721
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