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Kynurenine pathway metabolism following prenatal KMO inhibition and in Mecp2(+/−) mice, using liquid chromatography-tandem mass spectrometry
To quantify the full range of tryptophan metabolites along the kynurenine pathway, a liquid chromatography – tandem mass spectrometry method was developed and used to analyse brain extracts of rodents treated with the kynurenine-3-mono-oxygenase (KMO) inhibitor Ro61-8048 during pregnancy. There were...
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| Udgivet i: | Neurochem Int |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Pergamon Press
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5115650/ https://ncbi.nlm.nih.gov/pubmed/27623092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2016.09.012 |
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