Prenatal inhibition of the kynurenine pathway leads to structural changes in the hippocampus of adult rat offspring

Glutamate receptors for N-methyl-d-aspartate (NMDA) are involved in early brain development. The kynurenine pathway of tryptophan metabolism includes the NMDA receptor agonist quinolinic acid and the antagonist kynurenic acid. We now report that prenatal inhibition of the pathway in rats with 3,4-di...

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Detalhes bibliográficos
Publicado no:Eur J Neurosci
Main Authors: Khalil, Omari S, Pisar, Mazura, Forrest, Caroline M, Vincenten, Maria C J, Darlington, L Gail, Stone, Trevor W
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Developmental Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368408/
https://ncbi.nlm.nih.gov/pubmed/24646396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12535
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