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Prenatal activation of Toll-like receptors-3 by administration of the viral mimetic poly(I:C) changes synaptic proteins, N-methyl-D-aspartate receptors and neurogenesis markers in offspring

BACKGROUND: There is mounting evidence for a neurodevelopmental basis for disorders such as autism and schizophrenia, in which prenatal or early postnatal events may influence brain development and predispose the young to develop these and related disorders. We have now investigated the effect of a...

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Detalhes bibliográficos
Main Authors: Forrest, Caroline M, Khalil, Omari S, Pisar, Mazura, Smith, Robert A, Darlington, Lynda Gail, Stone, Trevor W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496691/
https://ncbi.nlm.nih.gov/pubmed/22681877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-5-22
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