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Prenatal Activation of Toll-Like Receptor-4 Dampens Adult Hippocampal Neurogenesis in An IL-6 Dependent Manner

Prenatal immune challenge has been associated with alteration in brain development and plasticity that last into adulthood. We have previously shown that prenatal activation of toll-like receptor 4 by lipopolysaccharide (LPS) induces IL-6-dependent STAT-3 signaling pathway in the fetal brain. Whethe...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Autor principal: Mouihate, Abdeslam
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927660/
https://ncbi.nlm.nih.gov/pubmed/27445700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00173
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