Interstrand cross-links are preferentially formed at the d(GC) sites in the reaction between cis-diamminedichloroplatinum (II) and DNA.

A DNA restriction fragment with convergent SP6 and T7 promoters has undergone reaction with cis-diamminedichloroplatinum(II) (cis-DDP) and was then used as a template for RNA synthesis in vitro. The T7 and SP6 RNA polymerases generate fragments of defined sizes. Analysis of the RNA fragments shows t...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Lemaire, M A, Schwartz, A, Rahmouni, A R, Leng, M
Format: Artigo
Langue:Inglês
Publié: 1991
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC51150/
https://ncbi.nlm.nih.gov/pubmed/2000402
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires