Interstrand cross-links are preferentially formed at the d(GC) sites in the reaction between cis-diamminedichloroplatinum (II) and DNA.

A DNA restriction fragment with convergent SP6 and T7 promoters has undergone reaction with cis-diamminedichloroplatinum(II) (cis-DDP) and was then used as a template for RNA synthesis in vitro. The T7 and SP6 RNA polymerases generate fragments of defined sizes. Analysis of the RNA fragments shows t...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Lemaire, M A, Schwartz, A, Rahmouni, A R, Leng, M
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1991
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51150/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2000402/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.5.1982
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