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YY1 binding association with sex-biased transcription revealed through X-linked transcript levels and allelic binding analyses

Sex differences in susceptibility and progression have been reported in numerous diseases. Female cells have two copies of the X chromosome with X-chromosome inactivation imparting mono-allelic gene silencing for dosage compensation. However, a subset of genes, named escapees, escape silencing and a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Chih-yu, Shi, Wenqiang, Balaton, Bradley P., Matthews, Allison M., Li, Yifeng, Arenillas, David J., Mathelier, Anthony, Itoh, Masayoshi, Kawaji, Hideya, Lassmann, Timo, Hayashizaki, Yoshihide, Carninci, Piero, Forrest, Alistair R. R., Brown, Carolyn J., Wasserman, Wyeth W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114649/
https://ncbi.nlm.nih.gov/pubmed/27857184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37324
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