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The frequent evolutionary birth and death of functional promoters in mouse and human
Promoters are central to the regulation of gene expression. Changes in gene regulation are thought to underlie much of the adaptive diversification between species and phenotypic variation within populations. In contrast to earlier work emphasizing the importance of enhancer evolution and subtle seq...
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| 發表在: | Genome Res |
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| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4579340/ https://ncbi.nlm.nih.gov/pubmed/26228054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.190546.115 |
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