The frequent evolutionary birth and death of functional promoters in mouse and human

Promoters are central to the regulation of gene expression. Changes in gene regulation are thought to underlie much of the adaptive diversification between species and phenotypic variation within populations. In contrast to earlier work emphasizing the importance of enhancer evolution and subtle seq...

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Dades bibliogràfiques
Publicat a:Genome Res
Autors principals: Young, Robert S., Hayashizaki, Yoshihide, Andersson, Robin, Sandelin, Albin, Kawaji, Hideya, Itoh, Masayoshi, Lassmann, Timo, Carninci, Piero, Bickmore, Wendy A., Forrest, Alistair R., Taylor, Martin S.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579340/
https://ncbi.nlm.nih.gov/pubmed/26228054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.190546.115
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