The frequent evolutionary birth and death of functional promoters in mouse and human

Promoters are central to the regulation of gene expression. Changes in gene regulation are thought to underlie much of the adaptive diversification between species and phenotypic variation within populations. In contrast to earlier work emphasizing the importance of enhancer evolution and subtle seq...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Young, Robert S., Hayashizaki, Yoshihide, Andersson, Robin, Sandelin, Albin, Kawaji, Hideya, Itoh, Masayoshi, Lassmann, Timo, Carninci, Piero, Bickmore, Wendy A., Forrest, Alistair R., Taylor, Martin S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579340/
https://ncbi.nlm.nih.gov/pubmed/26228054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.190546.115
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