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Deregulation of the miR-16-KRAS axis promotes colorectal cancer

KRAS plays a significant role in the etiology and progression of colorectal cancer (CRC), but the mechanism underlying this process has not been fully elucidated. In this study, we found that the KRAS protein levels were higher in CRC tissues than in the normal adjacent tissues, whereas its mRNA lev...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: You, Chaoying, Liang, Hongwei, Sun, Wu, Li, Jialu, Liu, Yanqing, Fan, Qian, Zhang, Haiyang, Yue, Xin, Li, Jing, Chen, Xi, Ba, Yi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114589/
https://ncbi.nlm.nih.gov/pubmed/27857191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37459
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