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Deregulation of the miR-16-KRAS axis promotes colorectal cancer

KRAS plays a significant role in the etiology and progression of colorectal cancer (CRC), but the mechanism underlying this process has not been fully elucidated. In this study, we found that the KRAS protein levels were higher in CRC tissues than in the normal adjacent tissues, whereas its mRNA lev...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: You, Chaoying, Liang, Hongwei, Sun, Wu, Li, Jialu, Liu, Yanqing, Fan, Qian, Zhang, Haiyang, Yue, Xin, Li, Jing, Chen, Xi, Ba, Yi
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114589/
https://ncbi.nlm.nih.gov/pubmed/27857191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37459
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