The Jun/miR-22/HuR regulatory axis contributes to tumourigenesis in colorectal cancer

BACKGROUND: Colorectal cancer (CRC) is a severe health problem worldwide. Clarifying the mechanisms for the deregulation of oncogenes and tumour suppressors in CRC is vital for its diagnosis, treatment, prognosis and prevention. Hu antigen R (HuR), which is highly upregulated in CRC, functions as a...

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Vydáno v:Mol Cancer
Hlavní autoři: Liu, Yanqing, Chen, Xiaorui, Cheng, Rongjie, Yang, Fei, Yu, Mengchao, Wang, Chen, Cui, Shufang, Hong, Yeting, Liang, Hongwei, Liu, Minghui, Zhao, Chihao, Ding, Meng, Sun, Wu, Liu, Zhijian, Sun, Feng, Zhang, Chenyu, Zhou, Zhen, Jiang, Xiaohong, Chen, Xi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5775639/
https://ncbi.nlm.nih.gov/pubmed/29351796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0751-3
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